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Showing 1 to 12 of 42 entries
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[The true story and advantages of the famous Hepatitis B virus core particles: Outlook 2016].

Molekuliarnaia biologiia

Pumpens P, Grens E.
PMID: 27668597
Mol Biol (Mosk). 2016 Jul-Aug;50(4):558-576. doi: 10.7868/S0026898416040091.

This review article is a continuation of the paper "Hepatitis B core particles as a universal display model: a structure-function basis for development" written by Pumpens P. and Grens E., ordered by Professor Lev Kisselev and published in FEBS...

[Role of DNA-dependent protein kinase in the HIV-1 replication cycle].

Molekuliarnaia biologiia

Knyazhanskaya ES, Shadrina OA, Anisenko AN, Gottikh MB.
PMID: 27668603
Mol Biol (Mosk). 2016 Jul-Aug;50(4):639-654. doi: 10.7868/S0026898416040078.

Human immunodeficiency virus type 1 (HIV-1) is among the best-studied viruses, but some aspects of HIV-1 biology remain obscure. The role of cell proteins in virus replication raises especially many questions. One of the proteins is DNA-dependent protein kinase...

[Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair].

Molekuliarnaia biologiia

Khodyreva SN, Lavrik OI.
PMID: 27668604
Mol Biol (Mosk). 2016 Jul-Aug;50(4):655-673. doi: 10.7868/S0026898416040030.

Poly(ADP-ribosyl)ation (PARylation) of proteins is one of the immediate cell responses to DNA damage and is catalyzed by poly(ADP-ribose) polymerases (PARPs). When bound to damaged DNA, some members of the PARP family are activated and use NAD^(+) as a...

[Remembering R.B. Khesin].

Molekuliarnaia biologiia

Lazurkin IuS.
PMID: 11969099
Mol Biol (Mosk). 2002 Mar-Apr;36(2):361-2.

No abstract available.

[Glucokinase and glucokinase regulatory proteins as molecular targets for novel antidiabetic drugs].

Molekuliarnaia biologiia

Rubtsov PM, Igudin EL, Tiulpakov AN.
PMID: 26299854
Mol Biol (Mosk). 2015 Jul-Aug;49(4):555-60. doi: 10.7868/S002689841504014X.

The impairment of glucose homeostasis leads to hyperglycemia and type-2 diabetes mellitus. Glucokinase (GK), an enzyme that catalyzes the conversion of glucose to glucose-6-phosphate in pancreatic ß-cells, liver hepatocytes, specific hypothalamic neurons, and intestine enterocytes, is a key regulator...

[Changes in the number of copies of genetic loci in gastric cancer].

Molekuliarnaia biologiia

Kit OI, Vodolazhsky DI, Kutilin DS, Gudueva EN.
PMID: 26299866
Mol Biol (Mosk). 2015 Jul-Aug;49(4):658-66. doi: 10.7868/S0026898415040096.

It is assumed that changes in the number of copies that belong to the basic mechanisms that control the expression of genes are important for malignization. Therefore, the characterization of these genes and the precise assessment of the number...

[Polymorphism of the bphA genes in bacteria destructing biphenyl/chlorinated biphenils].

Molekuliarnaia biologiia

Shumkova ES, Egorova DO, Boronnikova SV, Plotnikova EG.
PMID: 26299864
Mol Biol (Mosk). 2015 Jul-Aug;49(4):638-48. doi: 10.7868/S0026898415040151.

Polychlorinated biphenyls (PCBs) are persistent organic pollutants. Biphenyl 2,3-dioxygenase (BDO) is a key enzyme that determines the range of PCBs oxidized by a bacterial strain. BDO subunit α (BphA1) plays an essential role in substrate recognition and binding. The...

[In Process Citation].

Molekuliarnaia biologiia

[No authors listed]
PMID: 11033822
Mol Biol (Mosk). 2000 Sep;34(5):911-2.

No abstract available.

[DNA amplification using PCR with abutting primers].

Molekuliarnaia biologiia

Garafutdinov RR, Galimova AA, Sakhabutdinova AR, Vakhitov VA, Chemeris AV.
PMID: 26299863
Mol Biol (Mosk). 2015 Jul-Aug;49(4):628-37. doi: 10.7868/S0026898415040059.

DNA analysis of ñîmplex biological objects (wastewater, soil, archaeological and forensic samples, etc.) is currently of great interest. DNA of these objects is characterized by low suitability for research due to the violation of its integrity and chemical structure;...

[To the 80th anniversary of Lev Kisselev].

Molekuliarnaia biologiia

[No authors listed]
PMID: 27668595
Mol Biol (Mosk). 2016 Jul-Aug;50(4):547-548. doi: 10.7868/S0026898416040169.

No abstract available.

[S100A4, a link between metastasis and inflammation].

Molekuliarnaia biologiia

Ambartsumian N, Grigorian M.
PMID: 27668598
Mol Biol (Mosk). 2016 Jul-Aug;50(4):577-588. doi: 10.7868/S0026898416040029.

Chronic inflammation is acknowledged to be a hallmark of neoplasia - both in cancer initiation and metastasis progression. Here we summarise data suggesting that S100A4 is а trigger of the cascade events that establish an inflammatory milieu and provide...

[Inhibiting the pro-tumor and transcription factor FACT: Mechanisms].

Molekuliarnaia biologiia

Maluchenko NV, Chang HW, Kozinova MT, Valieva ME, Gerasimova NS, Kitashov AV, Kirpichnikov MP, Georgiev PG, Studitsky VM.
PMID: 27668600
Mol Biol (Mosk). 2016 Jul-Aug;50(4):599-610. doi: 10.7868/S002689841604008X.

Conventional antitumor therapy is often complicated by the emergence of the so-called cancer stem cells (CSCs), which are characterized by low metabolic rates and high resistance to almost all existing therapies. Many problems of clinical oncology and a poor...

Showing 1 to 12 of 42 entries